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Fospropofol Propofol Water-soluble prodrug → hydrolyzed by endothelial/hepatic alkaline phosphatases Lipid-soluble, manufactured as emulsified formulation (preservatives (like EDTA) added) Onset of action: 4-10 min 3-5 min Side Effects Paresthesias 50% 10–20% Pruritus 15–30 1–3 Respiratory depression 10 10–25 Hypotension 5 5–25 ...
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