The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in …

MAP kinases are activated within protein kinase cascades that regulate cell proliferation, differentiation, and death. In mammals, MAP kinases are grouped into three families: ERKs, …

Jul 21, 2025 · Learn how the MAPK signaling cascade relays information within cells to control key processes and why its disruption is a central factor in disease and therapy.

The MAPK signaling pathway is essential in regulating many cellular processes including inflammation, cell stress response, cell differentiation, cell division, cell proliferation, …

5 days ago · Overview of MAP Kinase signaling pathways, antibodies and related reagents, interactive pathway diagrams, and other technical resources.

The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration.

Dec 14, 2025 · The MAPK signal transduction cascades involve the coordination of a variety of extracellular signals that are initiated to control diverse cellular processes such as proliferation, …

There are three main MAPK signaling cascades: the extracellular signal-regulated kinase (ERK) pathway, the c-Jun N-terminal kinase (JNK) pathway and the p38 MAPK pathway.

Apr 29, 2025 · Cells rely on intricate signaling networks to maintain function and communication, with MAPK pathways playing a pivotal role. These pathways transmit signals from the cell …

MAPK signaling is a highly conserved pathway that transmits extracellular signals into the cell interior through a series of kinase cascades, including MKKK, MKK, and MAPK, regulating …