Researchers have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, revealing how this essential mitochondrial enzyme degrades RNA through an ...
This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...
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How Proteins Are Made: From DNA to Function
Proteins are essential biological molecules that perform a vast array of functions crucial for life, from catalyzing biochemical reactions and transporting molecules to providing structural support ...
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer ...
High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...
Scientists uncovered a surprising four-layer structure hidden inside the hippocampal CA1 region, one of the brain’s major centers for memory, navigation, and emotion. Using advanced RNA imaging ...
After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...
Preclinical in vivo data demonstrate hyper-precise mechanism directly targets the disease-causing mRNA repeats leading to correction of splicing ...
A hidden four-layer structure in the brain’s key memory hub has been revealed, reshaping how scientists understand learning ...
Researchers have used cryo-EM and computational tools to visualize ribozyme assembly, shedding light on life's most versatile ...
Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...
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