Medical Device and Diagnostic Industry (MD+DI)

Next-Gen Sequencing Is Going Global, And 2026 Could Be the Tipping Point

Revvity targets 2026 growth with multiomics, AI-powered base editing, NGS newborn screening, and immunotherapy advances.
IEEE

sigRGCN: A Robust Residual Graph Convolutional Network for scRNA-Seq Data Clustering

Abstract: Clustering is a crucial step in single-cell RNA sequencing (scRNA-seq) data analysis, facilitating the discovery of new cell types and the grouping of similar cells. Recently, graph ...
eLife

Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma

This valuable study presents an analysis of the gene regulatory networks that contribute to tumour heterogeneity and tumor plasticity in Ewing sarcoma, with key implications for other fusion-driven ...
eLife

TSvelo: Comprehensive RNA velocity by modeling the cascade of gene regulation, transcription and splicing

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...
Frontiers

MRI-based radiomic clustering identifies a glioblastoma subtype enriched for neural stemness and proliferative programs

Introduction: Glioblastoma (GBM) is a highly aggressive brain tumor with a median survival of only 15 months. A major challenge in GBM management is the pronounced inter- and intratumoral ...

Study uncovers and predicts widespread molecular changes in ALS brain cells

Researchers at the University of Toronto's Temerty Faculty of Medicine have found widespread genetic and protein changes in the brain cells of people with amyotrophic lateral sclerosis (ALS), which ...