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CDT1 overexpression suppresses DNA replication and triggers DNA damage linked to cancer, finds study
A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...
News-Medical.Net on MSN
New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...
The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...
Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...
AZoLifeSciences on MSN
Study uncovers principles guiding replication initiation across the human genome
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...
A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...
Scientists discovered that the first 100 base pairs of human genes are unusually prone to mutations, especially during the ...
Jyoti Vakhlu [email protected] From laws of inheritance to the molecule of heredity – a journey of scientific ...
The first 100 bases of many genes show excess mutations, revealing a major genomic weak spot that shapes disease risk and ...
Scientists at Children's Medical Research Institute (CMRI) have made a major discovery about cancer cells. This new ...
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