Glycosite-specific conjugation has emerged as a gold standard for developing next-generation Antibody-Drug Conjugates (ADCs) and other XDCs. However, most existing approaches are hindered by ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mammalian cells express three conjugatable ...

Royalty-free licenses let you pay once to use copyrighted images and video clips in personal and commercial projects on an ongoing basis without requiring additional payments each time you use that ...

At the American Society of Clinical Oncology meeting in June, researchers reported Phase II clinical study results for Genentech's antibody-drug conjugate trastuzumab-DM1. Although the company has ...

CHONGQING, China, Dec. 23, 2024 /PRNewswire/ -- On December 20, 2024, Porton Pharma Solutions (hereinafter referred to as "company" or "Porton") and Dragon Sail Pharmaceutical (Shanghai) Co., Ltd. (a ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Conjugation-mediated DNA delivery is the ...

In lab experiments, bacteria transferred plasmids with AMR genes in the presence of zinc at reduced or nonexistent rates. Stopping the transfer without killing microbes may help reduce AMR without ...

Genes responsible for antimicrobial resistance (AMR) can spread from microbe to microbe through circular genetic material called plasmids, and this lateral transfer occurs in the gut. This week in ...

Antimicrobial resistance is a growing threat. Bacteria exchange AMR genes in the gut via circular genetic material called plasmids. In lab experiments, bacteria transferred plasmids with AMR genes in ...

Antibody-drug conjugates (ADCs) represent an innovative class of potent anti-cancer agents. They combine the specificity of a monoclonal antibody with the potency of a cytotoxic drug, enabling ...

This story is part of a series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore tissues and organs damaged ...