Objective: Our goal was to evaluate the influence of quality control (QC) decisions using two genotype calling algorithms, CRLMM and Birdseed, designed for the Affymetrix SNP Array 6.0. Methods: ...
Single nucleotide polymorphisms (SNPs) are sequence variants in which two alternate bases occur at one position. The SNP Consortium is developing a dense map of SNPs in the hope that certain variants ...
A phase I, open-label, dose-escalation study to evaluate the safety, pharmacokinetics, and pharmacodynamics of oral azacitidine in subjects with myelodysplastic syndromes (MDS) or acute myelogenous ...
Genetic markers such as fragment length polymorphisms (RFLP), simple sequence repeat (SSR), and single-nucleotide polymorphisms (SNPs) provide unique identifiers for individual organisms. This aids ...
PAM50 intrinsic subtyping and pathologic responses to neoadjuvant trastuzumab-based chemotherapy in HER2-positive breast cancer. Background: Early detection and monitoring the progress of common ...
Affymetrix, Inc. has announced that it has released a data set based on extensive validation of novel SNPs from the 1000 Genomes Project. This data will give researchers access to more rare mutations ...
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