Liquid chromatography (LC) systems are the backbone of pharmaceutical and biopharmaceutical laboratories. However, with increasingly complex samples and efficiency pressures, scientists are seeking ...

This detailed overview explains the technical mechanisms of LC-MS proteomics, including peptide separation, ion generation, ...

Jessica Lin and Zhenqi (Pete) Shi from Genentech describe a novel machine learning approach to predicting retention times for ...

Researchers developed a liquid chromatography tandem mass spectrometry (LC-MS/MS) assay for the simultaneous measurement of 11 types of estrogen from song sparrows using derivatization with ...

High performance liquid chromatography, more commonly known by the acronym HPLC, is a method used to identify substances in a mixture. There are several types of HPLC, such as reversed-phase, ...

Fast protein liquid chromatography (FPLC) is, as the term implies, an effective (fast) liquid chromatography technique for the separation of protein molecules. The term also implies that the mobile ...

The wide range of chromatographic techniques share one common aim: to separate a material into its components. A material, your sample, is dissolved in a solvent, called the mobile phase. This mixture ...

Case in point: For more than a century, chromatography practitioners have been separating the components of chemical mixtures by using columns packed with various types of particulate matter. Recently ...

Sean Braet, a postdoctoral researcher at Penn State, installs a new trapping column for the liquid chromatography, which ...