Potassium channels can become nonconducting via inactivation at a gate inside the highly conserved selectivity filter (SF) region near the extracellular side of the membrane. In certain ligand-gated ...

Anu Tyagi, Tofayel Ahmed, Shi Jian, Saumya Bajaj, Seow Theng Ong, Stephanie Shee Min Goay, Yue Zhao, Igor Vorobyov, Changlin Tian, K. George Chandy, Shashi Bhushan Proceedings of the National Academy ...

Scientists are now able to "see" a structure that acts as an atomic-size sorter for cells. Without it, many important life functions—nerve signal firing, heartbeat, hormone secretion—could not occur.

They found that for the mutants displaying calcium blocking, one or two calcium ions are located at the bottom of the selectivity filter. They also discovered that magnesium (Mg 2+) and strontium (Sr ...

Ceramic resonators offer an attractive alternative to quartz crystals for stabilizing oscillation frequencies in many ...