Preclinical studies of the serotonin 2A (5-HT2A) antagonist deramciclane suggested an anxiolytic profile, which has not been unequivocally established in the clinic. The same receptor profile also ...

Animal models of human disease have extremely mixed results, and all too often they do not work well and accomplish their goals of helping humans. 1 One such procedure, the forced swim test, is a ...