An Imara drug that hits a novel target to treat rare, inherited hemoglobin disorders has failed two mid-stage studies, one for sickle cell disease and the other for beta thalassemia. The biotech ...

Could the solution for sickle cell disease lie with gene editing? New research, not yet in humans, suggests that a novel gene-editing strategy holds promise for people with this and other serious ...

Not long after birth, human babies transition from producing blood containing oxygen-rich fetal hemoglobin to blood bearing the adult hemoglobin protein. For children with sickle cell disease, the ...

A hemoglobin electrophoresis test is a blood test used to measure and identify the different types of hemoglobin in your bloodstream. Hemoglobin is the protein inside red blood cells responsible for ...

Red blood cell disorders refer to conditions that affect either the number or function of red blood cells (RBCs). Also known as erythrocytes, RBCs are concave, disc-shaped cells that move through ...

Adenosine base editing restarted fetal hemoglobin expression in cells from patients with sickle cell disease. Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease ...

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited ...

What Is an MCHC Blood Test? A mean corpuscular hemoglobin concentration (MCHC) blood test measures the amount of a protein called hemoglobin in your red blood cells. It’s one of many measurements ...

You might have wondered why some people with sickle cell disease seem to live relatively normal lives while others spend half their time in the hospital writhing in agony from pain crises. It’s the ...

An Hgb blood test measures a person’s hemoglobin levels. This protein helps red blood cells carry oxygen and keep cells and organs functioning. Low hemoglobin is known as anemia. Hemoglobin is also ...

CHICAGO — The Persian Gulf nation of Oman, located at the crossroads of Africa and Asia, presents a diverse ecosystem of patients with sickle cell disease (SCD), including a unique genotype specific ...

Haig Kazazian Jr., a pioneering scientist in the field of genetic medicine, died Jan. 19 of congestive heart failure. He was 84. Born to Armenian parents who survived genocide during World War I, ...