When conducting reproducible and interference-free analysis by liquid chromatography, the purity of the solvents used, particularly the purity of water, is crucial for the sensitivity of this method, ...

An interview with Dr. Michael Dong, about his upcoming talk at Pittcon. Why are stability-indicating methods important in pharmaceutical analysis? The stability-indicating assay is perhaps the single ...

The authors discuss the approach taken to develop a new calibration approach, its associated protocols, and how it can be used to calculate data. The use of open-access high-performance liquid ...

This study developed a High-Performance Liquid Chromatography (HPLC) method for the analysis of major withanolides in ashwagandha root and commercially available supplements. System suitability ...

This detailed overview explains the technical mechanisms of LC-MS proteomics, including peptide separation, ion generation, ...

Operating HPLC at higher than ambient temperatures can improve peak shapes and enable faster run times. Preheating the mobile phase is significant in high temperature liquid chromatography as the ...

The first part of an end-of-the-year review of LCGC International’s editorial coverage of HPLC 2025, which took place in Bruges from 19–23 June 2025 .

Synthetic oligonucleotides have been used as critical research reagents in the biotechnology industry since its beginning in the 1970s. Their increasing use first led to the formation of many core ...

Mass spec–based methods coupled with chromatography separation techniques are fundamental to success in proteomics research and biopharmaceutical development, and low-flow liquid chromatography has ...