Eclampsia was associated with distinct cerebrospinal fluid (CSF) biomarker profiles, indicating severe disruption of the blood-brain barrier (BBB) and increased neuroinflammation. This study was ...

If you find it hard to focus after a wakeful night, it’s because your brain is busy trying to catch up on crucial ...

Researchers led by CHLA’s Jonathan D. Santoro, MD, have identified signs of neuroinflammation and dysfunction of the blood-brain barrier among patients with Down syndrome Regression Disorder (DSRD). A ...

CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.

Damaged neurons leak proteins into bodily fluids, creating potential markers for neurodegenerative diseases including Alzheimer's. But one such prospect might be less clear-cut a measure of AD ...

Cerebrospinal fluid (CSF) is a clear and watery liquid that flows in and around the brain and spinal cord. Its functions include protecting parts of the nervous system, delivering nutrients and ...

The devastating consequences of mucopolysaccharidosis II (MPS II), also called Hunter syndrome, may soon become preventable ...

The properties of the blood-brain barrier serve a vital protective role, but they also keep drugs from reaching the organ. Big pharmaceutical companies have been making deals for technologies that ...