Synthetic oligonucleotides have been used as critical research reagents in the biotechnology industry since its beginning in the 1970s. Their increasing use first led to the formation of many core ...

Liquid chromatography-mass spectrometry (LC/MS) is a powerful integrated chemical technique that allows simultaneous separation of components from a mixture and analysis of each component based on ...

An introduction to the use of LC-MS and LC-MS/MS, with an emphasis on the analysis of drugs in biological matrices. This course is designed to provide basic knowledge and practical applications of ...

Biomarkers play an important role in drug development and help in the identification of disease-causing proteins found in blood, urine, body fluids, and tissue samples. The combination of liquid ...

Researchers developed a liquid chromatography tandem mass spectrometry (LC-MS/MS) assay for the simultaneous measurement of 11 types of estrogen from song sparrows using derivatization with ...

LC-MS is used to analyse pharmaceuticals across a variety of stages in their discovery and development. These stages include drug discovery, metabolism studies (in vitro and in vivo), and ...

This detailed overview explains the technical mechanisms of LC-MS proteomics, including peptide separation, ion generation, ...

When it comes to providing better care, having analytical techniques that can provide high specificity and greater sensitivity all while increasing the laboratories capabilities is essential.

Responding to a lack of sensitive analytical methods for detecting associated medications in complex wastewater matrices, ...

Quality assessment is crucial for determining the composition of clinically relevant compounds and drugs. This can be challenging using traditional analytical techniques, particularly if the ...